Article Title: A Study Of Antipsychotic Induced Tardive Dyskinesia In Indian Population

Author(s): Gupta Ravi, Bhatia Manjeet S.

Institute(s): The Psychiatry Department, University College of Medical Sciences and GTB Hospital, Dilshad Garden, Shahdara, Delhi-110095

Journal: Journal of Pakistan Psychiatric Society, 2006, Vol. 3, No. 1, p. 30–34

Correspondence Address: E-mail: manbhatia1@rediffmail.com; Tel: 0091-98101-61790

Abstract

Objective: This study was aimed at, to assess the point prevalence and risk factors in Indian population.

Design: Cross sectional comparative study.

Place and duration of study: The sample population was chosen from patients attending Psychiatry OPD of GTB Hospital during two months of the study (October 2004 to November, 2004).

Subjects and Methods: 62 subjects with history of exposure to antipsychotic drugs were included in this study. Their demographic data, illness related factors, and drug history were assessed. Tardive Dyskinesia (TD) was diagnosed according to DSM-IV-TR criteria. Significance of categorical variables was assessed by Chi-Square test and independent t-test was applied for comparison of numerical variables. Odds ratio was calculated using logistic regression.

Results: Point prevalence of TD in this sample was 16%. Advancing age in female gender predicted development of TD. Other known risk factors did not show any statistical significant effect.

Conclusion: Elderly females are at increased risk for development of TD. Point prevalence rate of 16% in mixed sample is fairly high and underscores the need for further studies in this area.

Key words: Tardive Dyskinesia, Neuroleptics, Risk factors.